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biologically active compounds from potent ganoderma pfeifferi dms 13239

机译:强效灵芝dms 13239的生物活性化合物

摘要

The present invention relates to novel biologically active compounds from fungi of the species Ganoderma pfeifferi DSM 13239, processes for their preparation, and their use. From the fruit body and mycelium of the species Ganoderma pfeifferi DSM 13239, extracts can be obtained which have antimicrobial activity and are suitable as preserving agents, for pharmaceutical and cosmetic preparations, for controlling infections, and for use in fish breeding. Antimicrobially active substances called ganomycins having activity against multiresistant germs are isolated from the extracts. The total synthesis of the ganomycins and their derivatization enables their use an antibiotics.
机译:本发明涉及来自灵芝菌DSM 13239的真菌的新型生物活性化合物,其制备方法及其用途。从灵芝种DSM 13239的子实体和菌丝体中,可以获得具有抗微生物活性并且适合用作防腐剂,用于药物和化妆品制剂,用于控制感染以及用于鱼类育种的提取物。从提取物中分离出具有抗多重耐药菌活性的被称为高霉素的抗菌活性物质。霉素的全合成及其衍生化使其能够使用抗生素。

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