use of a bactericidal / permeability increasing protein or biologically active analogue thereof for treatment of lipopolysaccharid associated.infections caused by gram negative bacteria

摘要

The present invention provides a method of inhibiting lipopolysaccharide (LPS)-mediated stimulation of cells. This method comprises contacting the cells, in the presence of a cell-stimulating amount of lipopolysaccharide, with bactericidal/permeability increasing protein (BPI) in an amount effective to inhibit cell stimulation.