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GENTE TRANSFER TO PANCREATIC EPITHELIC CELLS

机译:基因向胰腺上皮细胞的转移

摘要

The present invention relates to methods for selective somatic gene transfer into a patient's pancreatic or biliary epithelial cells. The methods of this invention comprise introducing the gene to be transferred, associated with an appropriate transfer vehicle, into the ductal system of either the pancreas or liver. More specifically, the invention relates to using these techniques to, treat genetic disease, such as cystic fibrosis, which are characterized by genetic defects in those epithelial cells. IMAGE
机译:本发明涉及将体细胞基因选择性转移到患者的胰腺或胆道上皮细胞中的方法。本发明的方法包括将要转移的基因与适当的转移载体结合,引入胰腺或肝脏的导管系统。更具体地,本发明涉及使用这些技术来治疗遗传性疾病,例如囊性纤维化,其特征在于那些上皮细胞中的遗传缺陷。 <图像>

著录项

  • 公开/公告号DE69431106T2

    专利类型

  • 公开/公告日2003-05-08

    原文格式PDF

  • 申请/专利号DE1994631106T

  • 发明设计人 WILSON M.;

    申请日1994-05-10

  • 分类号C12N15/86;C12N15/12;A61K48/00;

  • 国家 DE

  • 入库时间 2022-08-21 23:39:53

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