ANTITUMOR-ACTIVE BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS

摘要

PCT No. PCT/US97/12552 Sec. 371 Date Oct. 14, 1998 Sec. 102(e) Date Oct. 14, 1998 PCT Filed Jul. 22, 1997 PCT Pub. No. WO98/03518 PCT Pub. Date Jan. 29, 1998Bis-platinum(II) complexes with polymethylene derivatives, the method of making the complexes, and the use of the complexes for the treatment of tumors in mammals, are disclosed. The method of making the polymethylene derivatives, is also disclosed.