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Brief description of the formulation of an antifungal agent not - an irritant and non-toxic in the surfactant and aqueous compositions intended for cleansing the skin

机译:对用于清洁皮肤的表面活性剂和水性组合物中的非刺激性且无毒的抗真菌剂配方的简要说明

摘要

Cleansing the skin to reduce Candida albicans infections comprises applying a cosmetic composition containing, as amphoteric surfactant, undecylenamido-propyl betaine (I). (I) is N-(carboxymethyl)-N,N-dimethyl-3-((1-oxoundecenyl)amino)-1-propaminium hydroxide and is commercially available as Amphoram U (RTM). It is known to be useful against Pityrosporum ovalae and has been used in anti-dandruff shampoos FR99078683. The new compositions may also contain an anionic surfactant. The compositions preferably contain amphoteric surfactants (5-15 %), comprising (I) (5-7.5 %). The amount of anionic surfactant present may be 0-8.1 %, with the total amphoteric plus anionic surfactant content not exceeding 23.1 %. The compositions are preferably presented as gels for intimate cleansing, or as liquid soaps and lotions for cleansing the face.
机译:清洁皮肤以减少白色念珠菌感染包括施加含有十一碳烯酰胺基丙基甜菜碱(I)作为两性表面活性剂的化妆品组合物。 (I)是N-(羧甲基)-N,N-二甲基-3-((1-氧杂环烯基)氨基)-1-prop的氢氧化物,并且可以作为安菲拉姆U(RTM)商购获得。已知它可用于对抗椭圆孢子菌,并已用于去屑洗发剂FR99078683。新组合物还可包含阴离子表面活性剂。所述组合物优选包含两性表面活性剂(5-15%),包括(I)(5-7.5%)。阴离子表面活性剂的含量可以为0-8.1%,两性加阴离子表面活性剂的总含量不超过23.1%。该组合物优选以用于彻底清洁的凝胶或作为用于清洁面部的液体肥皂和洗剂的形式存在。

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