Nasal administration of 17-beta-estradiol, norethisterone, and partially methylated cyclodextrin, for treatment of menopausal symptoms

摘要

Aqueous solutions for nasal administration containing 2.2-2.8 mg/ml of 17- beta -estradiol, optionally in hydrated form, 3.5-4.5 mg/ml of norethisterone or its acetate, and 60-70 mg/ml of a partially-methylated cyclodextrin.