COMPOSITIONS FOR THE VECTORIZATION OF OLIGONUCLEOTIDES THROUGH THE HEMATOENCEPHALIC BARRIER AND THEIR USE FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM

摘要

The present invention relates to a compound consisting of at least one oligonucleotide linked to at least one vector peptide capable of allowing its transport across the blood-brain barrier (BBB). The invention also relates to the preparation of these compounds and pharmaceutical compositions containing them useful for the prevention and / or treatment of diseases of the central nervous system.