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Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide, and method for suppressing cancer cell growth using expression vector thereof
Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide, and method for suppressing cancer cell growth using expression vector thereof
The present invention provides a human tumor suppressor protein having the amino acid sequence of SEQ ID NO: 2; a polynucleotide encoding the tumor suppressor protein; an expression vector containing the polynucleotide; a microorganism or animal cell transformed with the expression vector; a method for suppressing proliferation of a cancer cell which comprises introducing the expression vector into a cancer cell to induce apoptosis thereof; and a pharmaceutical composition for preventing or treating cancer which comprises a therapeutically effective amount of the polynucleotide and a pharmaceutically acceptable carrier.
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机译:本发明提供了具有SEQ ID NO:2的氨基酸序列的人肿瘤抑制蛋白。编码肿瘤抑制蛋白的多核苷酸;含有多核苷酸的表达载体;用表达载体转化的微生物或动物细胞;一种抑制癌细胞增殖的方法,该方法包括将表达载体引入癌细胞以诱导其凋亡。预防或治疗癌症的药物组合物,其包含治疗有效量的多核苷酸和药学上可接受的载体。
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