The geometric isomers and derivatives-1-deoxy-podophyllotoxin replacement 4'-demethyl -4'-O- novel anticancer agent compositions comprising the same, and manufacturing method thereof

摘要

The present invention provides a novel 4'-demethyl-4'-O-substituted-1-deoxypodophyllotoxin derivative, a geometric isomer thereof, a process for the preparation thereof, and an anticancer composition comprising the same.