The diagnosis with the be inherited principal parameter of large compound internal of histocompatibility

摘要

The present invention describes nucleic acids for the diagnosis of a set of genetic parameters within the major histocompatibility complex (MHC), comprising a segment that is inversely complementary or identical to a chemically pretreated genomic DNA and that is at least 20 base pairs long as well as a set of oligomer probes (oligonucleotides and/or PNA oligomers), which serve for the detection of the cytosine methylation state in nucleic acids. These probes are particularly suitable for the diagnosis of genetic parameters within the MHC.