Use of 5-thio-, sulfinyl- and sulfonylpyrazolo 3,4-b -pyridine as cyclin dependent kinase inhibitors

摘要

The present invention describes compounds of formula (I):and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and n are as defined above. Compounds of formula (I) are protein kinase inhibitors and are useful in the treatment of proliferative diseases, for example, cancer, inflammation and arthritis. They may also be useful in the treatment of Alzheimer's disease and cardiovascular disease.