Endogenous human G protein-coupled receptors and non-endogenous type

摘要

Relates to transmembrane receptors, and more specifically human G protein-coupled receptor of unknown endogenous ligand present invention disclosed in this patent specification is, and relates to ("orphan GPCR receptors") Most specifically, mutation of the human GPCR for evidence of constitutive activity on the (non-endogenous) type.