The inflammation of the skin and the be inherited decisive factor for immunity

摘要

The invention relates to the localisation of genetic factors associated with dermal inflammation and immunity to particular regions of the human genome. In particular, there are described methods of determining the genetic susceptibility of an individual to disease conditions involving dermal inflammation and immunity, especially but not exclusively atopic dermatitis, methods for the identification of polymorphic alleles which confer susceptibility to conditions involving dermal inflammation and immunity and methods for the identification of a human genes which contribute to or are responsible for the manifestation of disease conditions involving dermal inflammation and immunity.