Screening method null of revelation guidance and control substance of thermal shock

摘要

HSP expression inducing inhibitor having the process of examining expression of reporter gene product in the presence of the subject compound using the cell line transformed by the vector which connected reporter gene downstream of promoter of heat shock protein (HSP) gene Screening method for expression inducing agent, expression inducing control agent such as expression inducer, expression inducing enhancer, expression inducing inhibitor, expression inducing agent, expression inducing enhancer, and expression inducible inhibitor of HSP that can be selected by such screening method A pharmaceutical composition comprising an inducer and an expression inducible enhancer is provided.