Method for analyzing inhibition of ftsz polymerization using fluorescence assay technique

摘要

A method for identifying chemical inhibitors of FtsZ polymerization using a direct fluorescence detection technique. The technique is based on the physical separation of fluorescently-labeled polymers of FtsZ from monomeric forms. This invention has both research and clinical applications in the identification of inhibitors of FtsZ polymerization as potential antibacterial agents.