OCT1p, a protein having homology to the organic and sugar transporter family of proteins, and uses thereof

摘要

Novel OCTlp polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length OCT-like proteins, the invention further provides isolated OCTlp fusion proteins, antigenic peptides and anti-OCTlp antibodies. The invention also provides OCTlp nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an OCTlp gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.