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Overcoming DAPA aminotransferase bottlenecks in biotin vitamers biosynthesis
Overcoming DAPA aminotransferase bottlenecks in biotin vitamers biosynthesis
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机译:克服生物素维他命生物合成中的DAPA氨基转移酶瓶颈
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摘要
A method is disclosed for the increased production of biotin and the biotin precursor dethiobiotin using a bacterium that produces a lysine-utilizing DAPA aminotransferase. The method involves the use of a bacterium that is either grown in the presence of lysine or deregulated for lysine biosynthesis.
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