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Methods for regulating bud-hypha transitions and cAMP levels in Candida albicans
Methods for regulating bud-hypha transitions and cAMP levels in Candida albicans
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机译:调节白色念珠菌芽菌丝过渡和cAMP水平的方法
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摘要
The infection of a mammalian host by a microorganism can be prevented or treated through the alteration of the C. albicans homologue of the high affinity phosphodiesterase, PDE2, gene and/or the adenylate cyclase-associated protein gene. These methods may be used in the identification, prevention or treatment of microbial infection of mammalian hosts such as immunocompromised or immunosuppressed humans, for example, those having AIDS or undergoing transplantation or anti-cancer therapy.
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