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Compositions and methods for treating trail-resistant cancer cells
Compositions and methods for treating trail-resistant cancer cells
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机译:用于治疗耐药性癌细胞的组合物和方法
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摘要
The present invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a cellular FLICE-like inhibitory protein (cFLIP) gene, comprising a complementary RNA strand which is substantially identical to at least a part of a cFLIP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for inhibiting the expression of a cFLIP gene in a cell, methods for improving the effectiveness of an apoptosis-inducing drug, and methods for treating cancer using the pharmaceutical composition.
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