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Sequence and method for genetic engineering of proteins with cell membrane translocating activity
Sequence and method for genetic engineering of proteins with cell membrane translocating activity
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机译:具有细胞膜易位活性的蛋白质的基因工程序列和方法
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摘要
The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.
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