embedded image;are useful for treating the cognitive deficits due to aging, stroke, head trauma, Alzheimer's disease or other neurodegenerative diseases, or schizophrenia. The compounds of the invention are also useful for the treatment of disorders such as anxiety, aggression and stress, and for the control of various physiological phenomena, such as appetite, thermoregulation, sleep and sexual behavior."/> Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopentaanaphthalene as 5-HT1A antagonists
首页> 外国专利> Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopentaanaphthalene as 5-HT1A antagonists

Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopentaanaphthalene as 5-HT1A antagonists

机译:7,5-二氢-1,6,9-三氧杂-3-氮杂-环戊萘的氮杂环杂环烷基甲基衍生物作为5-HT1A拮抗剂

摘要

Compounds of the formula embedded image;are useful for treating the cognitive deficits due to aging, stroke, head trauma, Alzheimer's disease or other neurodegenerative diseases, or schizophrenia. The compounds of the invention are also useful for the treatment of disorders such as anxiety, aggression and stress, and for the control of various physiological phenomena, such as appetite, thermoregulation, sleep and sexual behavior.
机译:分子式为 “嵌入式图像” ;可用于治疗由于衰老,中风,头部外伤,阿尔茨海默氏病或​​其他神经退行性疾病或精神分裂症引起的认知缺陷。本发明的化合物也可用于治疗疾病,例如焦虑,攻击和压力,并用于控制各种生理现象,例如食欲,体温调节,睡眠和性行为。

著录项

  • 公开/公告号US6815448B2

    专利类型

  • 公开/公告日2004-11-09

    原文格式PDF

  • 申请/专利权人 WYETH;

    申请/专利号US20020132237

  • 发明设计人 GARY P. STACK;MEGAN TRAN;

    申请日2002-04-25

  • 分类号C07D4980/40;C07D5190/00;A61K314/24;A61P252/80;

  • 国家 US

  • 入库时间 2022-08-21 23:17:59

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