Methods of processing tagged MRI data indicative of tissue motion including 4-D LV tissue tracking

摘要

A method for tracking motion of tissue in three or four dimensions by obtaining a model from imaging data having tag planes from which a grid of control points may be defined. First, knot planes are calculated from the grid of control points of the imaging data. Next, the knot planes are fitted to the tag planes to obtain the model of the tissue. Next, motion of tissue in three or four dimensions is represented with the model of the tissue.;Also disclosed is a method for reconstructing tag surfaces with B-spline surfaces from imaging data having sets of image slices with tag data and calculating motion between the B-spline surfaces, comprising the steps of:;reconstructing at least a first B-spline surface from B-spline curves corresponding to a first tag surface from a first set of image slices;;reconstructing at least a second B-spline surface from B-spline curves corresponding to a second tag surface from a second set of image slices; and;calculating motion between B-spline surfaces.;Also disclosed is a method for warping a first area in a first image slice of imaging data containing tag lines into a corresponding second area in a second image slice of imaging data successive in time to interpolate a dense displacement vector field using smoothing splines. First, find coordinates of the tag lines in both slices of imaging data. Next, reconstruct a dense displacement vector field with smoothing splines using coordinates of the tag lines. As a result, images indicating strain and images having indicators of tissue motion are provided.