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Methods and compositions for nucleic acid ligands against Shiga toxin and/or Shiga-like toxin
Methods and compositions for nucleic acid ligands against Shiga toxin and/or Shiga-like toxin
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机译:抗志贺毒素和/或志贺样毒素的核酸配体的方法和组合物
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摘要
The present invention concerns methods of preparing nucleic acid ligands against Shiga toxin and/or Shiga-like toxin, compositions comprising nucleic acid ligands that bind Shiga toxin and/or Shiga-like toxin, nucleic acid ligands comprising contiguous nucleotide sequences selected from SEQ ID NO:1 through SEQ ID NO:11 and methods of use of such ligands for detection and/or neutralization of Shiga toxin and/or Shiga-like toxin.
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机译:本发明涉及制备抗志贺氏菌毒素和/或志贺氏样毒素的核酸配体的方法,包含与志贺氏菌毒素和/或志贺氏样毒素结合的核酸配体的组合物,包含选自SEQ ID NO:1的连续核苷酸序列的核酸配体1:1至SEQ ID NO:11以及使用此类配体检测和/或中和志贺毒素和/或志贺样毒素的方法。
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