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Transdermal and topical administration of local anesthetic agents using basic enhancers
Transdermal and topical administration of local anesthetic agents using basic enhancers
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机译:使用基本增强剂透皮和局部给药局部麻醉剂
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摘要
Compositions and transdermal systems are provided for enhancing the permeability of skin or mucosal tissue to topical or transdermal application of local anesthetic agents. The compositions and systems include a base in order to increase the flux of the agent through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. The permeation enhancer can be an inorganic or organic base. Methods of use are also described.
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