首页>
外国专利>
Identification of a region of the major surface glycoprotein (MSG) gene of human Pneumocystis carinii
Identification of a region of the major surface glycoprotein (MSG) gene of human Pneumocystis carinii
展开▼
机译:鉴定人卡氏肺孢子虫主要表面糖蛋白(MSG)基因区域
展开▼
页面导航
摘要
著录项
相似文献
摘要
Particularly sensitive techniques for the detection of P. carinii in clinical samples are disclosed. These techniques relate to the PCR amplification and/or detection of human-P. carinii major surface glycoprotein (MSG) gene sequences. Also disclosed are seven novel genes encoding human-P. carinii MSG, and the proteins encoded for by these genes. These genes provide proof that human-P. carinii MSG is encoded for by a highly conserved gene family, and that the conesponding proteins have a very highly conserved region of about 100 amino acids near their C-terminal end. This highly conserved carboxy-terminal region has a significantly different sequence than that found in rat-derived MSG.
展开▼