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Methods for the synthesis of complex reduced isoindole, isooxyindole and isooxyquinoline libraries
Methods for the synthesis of complex reduced isoindole, isooxyindole and isooxyquinoline libraries
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机译:复杂的还原异吲哚,异氧吲哚和异氧喹啉文库的合成方法
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摘要
Disclosed are methods of synthesizing libraries of diverse complex hexahydroisoindole, hexahydroisooxyindole and octahydroisooxyquinoline compounds through the use of a facile intramolecular Diels Alder reaction. The invention is further directed to methods for synthesizing the libraries on solid supports. The invention is further directed to methods for identifying and isolating such hexahydroisoindole, hexahydroisooxyindole and octahydroisooxyquinoline compounds with useful and diverse activities from such libraries.
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