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Methods of ranking oligonucleotides for specificity using wash dissociation histories
Methods of ranking oligonucleotides for specificity using wash dissociation histories
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机译:使用洗涤解离历史对寡核苷酸进行特异性排名的方法
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摘要
The present invention provides methods and systems, particularly computer systems, for determining the relative specificity with which a particular polynucleotide molecule hybridizes to a polynucleotide probe. For example, the methods and systems of the invention enable a user to compare the specificity with which different polynucleotides hybridize to a given probe and/or rank these polynucleotides according to their specificity to that probe. The methods and systems of the invention also enable a user to compare the specificity with which a particular polynucleotide hybridizes to different probes, and/or rank those different probes according to their specificity for that particular polynucleotide.
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