首页> 外国专利> Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human

Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human

机译:外源多核苷酸序列在脊椎动物,哺乳动物,鱼类,鸟类或人类中的表达

摘要

A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate. The method can be used to deliver a therapeutic polypeptide to the cells of the vertebrate, to provide an immune response upon in vivo translation of the polynucleotide, to deliver antisense polynucleotides, to deliver receptors to the cells of the vertebrate, or to provide transitory gene therapy.
机译:一种将分离的多核苷酸递送到脊椎动物的细胞内部的方法,包括将分离的多核苷酸间质地引入到脊椎动物的组织中,在该组织中多核苷酸被组织的细胞吸收并对其产生治疗作用。脊椎动物。该方法可用于将治疗性多肽递送至脊椎动物的细胞,在多核苷酸的体内翻译后提供免疫应答,递送反义多核苷酸,将受体递送至脊椎动物的细胞或提供瞬时基因。治疗。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号