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Carbamate compounds for use in preventing or treating neuropathic pain and Pain associated with Headache and headache migranosa acuminate

机译:氨基甲酸酯类化合物,用于预防或治疗与头痛和偏头痛的尖锐湿疣相关的神经性疼痛和疼痛

摘要

Use of a therapeutically effective amount of an enantiomer of formula (1) substantially free of other enantiomers or enantiomeric mixture where one enantiomer of formula (1): phenyl predominates where X is replaced with one or five independently Halogen Atoms Selected from the group consisting of Fluorine, Chlorine, Bromine and iodine; and,R1 and R2 are independently selected from the group consisting of hydrogen and alkyl c1-4 alkyl of C1, where 4 is replaced with phenyl optionally substituted phenyl (Where is optionally independently with substituents selected from the group consisting of den Halogen, alkyl Of c1-4 alkoxy, C1 - 4, amino, Nitro and cyano)For the manufacture of a Medicament for preventing or treating neuropathic pain and Pain associated with Headache and migranosa acuminate.
机译:使用治疗有效量的基本上不含其他对映异构体或对映异构体混合物的式(1)对映异构体,其中一种式(1)对映异构体:苯基占优势,其中X被一个或五个独立的卤素原子取代氟,氯,溴和碘;并且,R 1和R 2独立地选自氢和C 1的烷基C 1-4烷基,其中4被任选取代的苯基取代(其中任选地独立地选自由以下组成的组的取代基:卤素,烷基C 1-4烷氧基,C 1-4,氨基,硝基和氰基)用于制造用于预防或治疗与头痛和偏头痛相关的神经性疼痛和疼痛的药物。

著录项

  • 公开/公告号AR034786A1

    专利类型

  • 公开/公告日2004-03-17

    原文格式PDF

  • 申请/专利权人 ORTHO-MCNEIL PHARMACEUTICAL INC.;

    申请/专利号AR2002P102647

  • 发明设计人

    申请日2002-07-15

  • 分类号A61K31/325;A61P29/02;

  • 国家 AR

  • 入库时间 2022-08-21 23:12:24

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