Solution for intravenous administration, and method for producing an amiodarone solution suitable for intravenous administration

摘要

"INTRAVENOUS ADMINISTRATION SOLUTION AND METHOD FOR PRODUCING AN ADMINISTRATIVE AMIODARONE SOLUTION". A premixed parenteral solution for intravenous administration is presented, having amiodarone as an active ingredient solubilized in a water for injection solution and about 0.4 to 12 mg / ml nonionic surfactant over a concentration range of 0 ° C. 2 to 6 mg / ml. A solution optionally may include an osmotic agent. No dilution of the solution is required prior to administration to a patient and the sterile packaged solution has an initial pH within the range of about 2.9 to about 3.2, preferably about 3.1. Additionally, a method for producing an amiodarone solution suitable for intravenous administration is further presented.