Isolated peptide or polypeptide and derivatives thereof, nucleic acid encoding the same, vaccine copying the same, nucleic acid encoding the same, vector comprising said nucleic acid, host cell comprising said nucleic acid, pharmaceutical composition comprising said peptide or polypeptide, method for treating or preventing cancer using said pharmaceutical composition and method for inducing or magnifying an immune response using said pharmaceutical composition

摘要

"Peptide or polypeptide ISOLATED AND THEIR DERIVATIVES, nucleic acid encoding the same, VACCINE COPREENDENDO THE SAME, nucleic acid encoding the same, UNDERSTAND VECTOR SUCH nucleic acid, host cell UNDERSTAND SUCH Nucleic Acid, Pharmaceutical Composition UNDERSTAND SUCH peptide or polypeptide, METHOD FOR TREATING OR PREVENTION OF CANCER USING SUCH PHARMACEUTICAL COMPOSITION AND METHOD FOR INDUCING OR MAGNIFYING AN IMMUNOLOGICAL RESPONSE USING SUCH PHARMACEUTICAL COMPOSITION ". An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO: 1), found in the secreted form of human MUC1, which magnifies an immune response when administered to a mammal, peptide-containing compositions, peptide-producing host cells and methods of use. the same. The peptide or polypeptide may be conjugated to a carrier protein and administered as part of a vaccine or immunogenic composition for the prevention or treatment of a disease or disorder.