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Carbamate compounds for use in the prevention or treatment of neuropathic pain and cluster and hemicranial headache pain
Carbamate compounds for use in the prevention or treatment of neuropathic pain and cluster and hemicranial headache pain
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机译:氨基甲酸酯化合物,用于预防或治疗神经性疼痛,丛集性和半颅性头痛
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摘要
"CARBAMATE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NEUROPATHIC PAIN AND PAIN ASSOCIATED PAIN IN HEAD AND HEMICRANIA". The present invention relates to a method for preventing or treating neuropathic pain and cluster and hemicranial headache pain comprising administering to a subject in need thereof a therapeutically effective amount of a Formula (I) enantiomer substantially free of other disorders. enantiomers or an enantiomeric mixture where a Formula (I) enantiomer predominates: where phenyl is substituted at X by one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1-1 and R2 are independently selected from the group consisting of hydrogen and C1-4 alkyl; where C 1 - C 4 -C 4 alkyl is optionally substituted by phenyl (where phenyl is optionally substituted by substituents independently selected from the group consisting of hydrogen, halogen, C 1 -C 4 alkyl, C 1 - C 1-4 alkoxy, amino, nitro and cyano).
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