首页> 外国专利> A compound or a pharmaceutically acceptable salt thereof, composition, methods for treating or preventing a dopamine-relieved inhibition of dopamine resorption inhibition, attention deficit disorder, depression, obesity, parkinson's disease, a dependence, and a tic disorder, and, method for obtaining a compound

A compound or a pharmaceutically acceptable salt thereof, composition, methods for treating or preventing a dopamine-relieved inhibition of dopamine resorption inhibition, attention deficit disorder, depression, obesity, parkinson's disease, a dependence, and a tic disorder, and, method for obtaining a compound

机译:化合物或其药学上可接受的盐,组合物,治疗或预防多巴胺减轻的多巴胺吸收抑制,注意缺陷障碍,抑郁症,肥胖症,帕金森氏病,依赖性和抽动症的抑制方法以及获得方法化合物

摘要

"COMPOSITION OR PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME, COMPOSITION, METHODS FOR TREATMENT OR PREVENTION OF A DISEASE RELIEFED BY INHIBITION OF DOPAMINE REHABILITATION, DISEASE OF ATHENS DUE DISEASE, ATHENS DUE DISORDER, OF DEPENDENCE, AND A TICKET DISTURBANCE, AND METHOD FOR A COMPOUND. " The present invention relates to (-) -1- (3,4-dichlorophenyl) -3-azabicyclo [3.1.0] hexane and pharmaceutically acceptable salts thereof, compositions comprising (-) - 1- (3,4-dichlorophenyl) dichlorophenyl) -3-azabicyclo [3.1.0] hexane or a pharmaceutically acceptable salt thereof, and methods for treating or preventing a disorder relieved by dopamine reuptake inhibition. In one embodiment, the disorder is attention deficit disorder, depression, obesity, Parkinson's disease, a tic disorder, or a dependence disorder. The (-) - 1- (3,4-dichlorophenyl) -3 azabicyclo [3.1.0] hexane or pharmaceutically acceptable salt thereof is preferably substantially free of its corresponding (+) enantiomer.
机译:“通过抑制多巴胺的复健,减轻因雅典疾病而引起的疾病,减轻因雅典疾病而引起的疾病,依赖,和ICK病的组成或药物可接受的盐,组成,治疗或预防疾病的方法本发明涉及(-)-1-(3,4-二氯苯基)-3-氮杂双环[3.1.0]己烷及其药学上可接受的盐,所述组合物包含(-)-1-(3,4-二氯苯基) )二氯苯基)-3-氮杂双环[3.1.0]己烷或其药学上可接受的盐,以及治疗或预防通过多巴胺重摄取抑制而缓解的疾病的方法。在一个实施方案中,该疾病是注意力缺陷疾病,抑郁症,肥胖症,帕金森氏病,抽动症或依赖性疾病。 (-)-1-(3,4-二氯苯基)-3氮杂双环[3.1.0]己烷或其药学上可接受的盐优选基本上不含其相应的(+)对映异构体。

著录项

  • 公开/公告号BR0212147A

    专利类型

  • 公开/公告日2004-08-24

    原文格式PDF

  • 申请/专利权人 DOV PHARMACEUTICAL INC.;

    申请/专利号BR20020212147

  • 发明设计人 ARNOLD STAN LIPPA;JOSEPH WILLIAM EPSTEIN;

    申请日2002-08-14

  • 分类号A61K31/403;C07D209/52;

  • 国家 BR

  • 入库时间 2022-08-21 23:12:02

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