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Methods of Detecting Autoantibodies in Patients Suffering from Rheumatoid Arthritis, Peptide, and Assay Kit

机译:类风湿关节炎患者自身抗体的检测方法,多肽和检测试剂盒

摘要

"METHODS OF DETECTING AUTO-ANTIBODIES OF PATIENTS SUFFERING FROM RUMATOID ARTHRITIS, PEPTIDE AND TEST KIT". The present invention relates to the method of detecting autoantibodies of patients suffering from rheumatoid arthritis. For this purpose, according to the invention at least two peptide units are used, of which at least one peptide unit comprises a non-derivative part of (pro) filaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and moiety. A peptide moiety comprising motif XG, and a peptide moiety comprising motif XnonG, wherein X is a citrulline or analog thereof, and nonG is a different amino acid from glycine.
机译:“检测患有类风湿关节炎,肽和试剂盒的患者自身抗体的方法”。本发明涉及检测类风湿性关节炎患者自身抗体的方法。为此,根据本发明,使用至少两个肽单元,其中至少一个肽单元包含(原)丝蛋白,纤维蛋白,纤维蛋白原,波形蛋白,细胞角蛋白1和细胞角蛋白9的非衍生物部分和部分。包含基序XG的肽部分和包含基序XnonG的肽部分,其中X是瓜氨酸或其类似物,并且nonG是与甘氨酸不同的氨基酸。

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