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Use of an enterobacterial OmpA protein for specific measurement for antigen-presenting cells

机译:肠细菌OmpA蛋白用于抗原呈递细胞的特异性检测的用途

摘要

The invention concerns the use of an enterobacterium protein OmpA, preferably Klebsiella pneumoniae P40 protein, for specific targeting of a biologically active substance associated therewith towards antigen-presenting cells, in particular human dendritic cells. The invention also concerns the use of the OmpA protein for preparing a pharmaceutical composition for preventing and/or treating diseases, in particular cancers related to a tumour-associated antigen, autoimmune diseases or infectious diseases.
机译:本发明涉及肠杆菌蛋白OmpA,优选肺炎克雷伯菌(Klebsiella pneumoniae)P40蛋白,用于将与其相关的生物活性物质特异性靶向抗原呈递细胞,特别是人树突状细胞。本发明还涉及OmpA蛋白在制备用于预防和/或治疗疾病,特别是与肿瘤相关抗原有关的癌症,自身免疫性疾病或传染性疾病的药物组合物中的用途。

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