Soluble functional derivative of ICAM-1, recombinant DNA molecule and method for preparing said derivative, pharmaceutical composition containing such derivative and the use of the derivative to prepare such preparation, and ...

摘要

The present invention relates to intercellular adhesion molecules (ICAM-1) which are involved in the process through which lymphocytes recognize and migrate to sites of inflammation as well as attach to cellular substrates during inflammation. The invention is directed toward such molecules, screening assays for identifying such molecules and antibodies capable of binding such molecules. The invention also includes uses for adhesion molecules and for the antibodies that are capable of binding them.