首页> 外国专利> thype 4-hydroxy coumarin anticoagulant compositions, process for their preparation, enticides (bait) and includes such anticoagulants and process control of rodents using them.

thype 4-hydroxy coumarin anticoagulant compositions, process for their preparation, enticides (bait) and includes such anticoagulants and process control of rodents using them.

机译:thype 4-羟基香豆素抗凝剂组合物,其制备方法,除草剂(诱饵)(包括此类抗凝剂)和使用它们的啮齿动物的过程控制方法。

摘要

Compounds having blood-anticoagulant properties of the general molecular formula: IMAGE (II) in which Z represents a halogen atom, preferably a chlorine atom, and n is 0, 1 or 2 and R4 represents either (1) a grouping which comprises a phenylene radical attached directly or indirectly to the tetralin ring and having in the para position (with respect to such attachment) an electron-withdrawing atom or group whose rotational volume substantially does not exceed that of a phenyl group and which forms together with said phenylene radical a polarizable structure, or (2) a grouping selected from: IMAGE +TR IMAGE or (3) a grouping which comprises a phenylene radical attached directly to the tetralin ring and having in the para position (with respect to such attachment) a substituted furanyl or thiophenyl radical attached thereto directly or through oxygen and/or methylene, said furanyl or thiophenyl radical having such an electron-withdrawing atom or group as a substituent in a position forming with the furanyl or thiophenyl radical a polarizable structure, compounds of the type (1) in which R4 contains two phenylene radicals linked essentially linearly by an aliphatic chain comprising a methylene radical or radicals and optionally at least one oxygen or sulphur atom being preferred. Also included are the processes for the preparation of such compound; rodenticidal compositions containing them; and a method for controlling rodents by applying such a composition.
机译:具有通式抗血液凝结特性的化合物:<图像>(II),其中Z表示卤原子,优选氯原子,且n为0、1或2,R4表示(1)直接或间接连接到四氢萘环上并在对位(相对于这种连接)具有吸电子原子或基团的亚苯基,该吸电子原子或基团的旋转体积基本上不超过苯基,并且与所述亚苯基一起形成可极化结构的基团,或(2)选自以下的基团: + TR 或(3)包含直接连接到四氢化萘环上并具有对位的亚苯基的基团取代基)直接或通过氧和/或亚甲基连接于其上的取代的呋喃基或噻吩基,所述呋喃基或噻吩基具有作为吸电子原子或基团的取代基。在与呋喃基或硫代苯基形成一个可极化结构的位置上,其中R4含有两个亚苯基的化合物是优选的,其中R4通过一个或多个亚甲基基团和任选地至少一个氧或硫原子基本上通过脂族链线性连接。 。还包括制备这种化合物的方法。含有它们的杀鼠组合物;以及通过施用这种组合物来控制啮齿动物的方法。

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