首页> 外国专利> ANTI-TUMOR, ANTI-VIRUS, ANTI-BACTERIAL, ANTI-PARASITIC, ANTI-INFLAMMATORY, IMMUNE-MODULATING AND ANTI-FUNCTION MEDICINE, METHOD FOR ITS MANUFACTURE AND ANTI-FUNCTION MEDICINE

ANTI-TUMOR, ANTI-VIRUS, ANTI-BACTERIAL, ANTI-PARASITIC, ANTI-INFLAMMATORY, IMMUNE-MODULATING AND ANTI-FUNCTION MEDICINE, METHOD FOR ITS MANUFACTURE AND ANTI-FUNCTION MEDICINE

机译:抗肿瘤,抗病毒,抗细菌,抗寄生虫,抗炎,免疫调节和抗功能药物,其制备方法和抗功能药物

摘要

The invention relates to medicine, pharmocology and to the chemical and pharmaceutical industry. The aim of the invention is to develop a new medicinal preparation having high activity and having a large range of the above mentioned non-specific pharmacological action, and a production method for all presently known dosage forms. The novelty of the invention lies in a biologically active part of the preparation which contains a mixture of acridoneacetic acid or the derivatives thereof with monosubstituted ethers of monosaccharides, the biologically active part being heat treated together with a pharmaceutically acceptable carrier at temperatures ranging from 80 DEG C to 120 DEG C. The medicinal preparation containing ANANDIN exhibits higher efficiency. ANANDIN is embodied in the form of a mixture of N- acridoneacetic acid (glucoaminopropylcarbacridone) and 3-0 (N,N-dimethylamino-n-propyl)-1.2:5.6- di-O-isopropylidene- alpha , D-glucofuranose (dimethylaminopropylglucofuranose). The inventive medicinal preparation is embodied in the form of all known dosage forms. Six series of examples for producing the preparation and the dosage forms thereof, detailed information on the experimental estimate of all biological activities enumerated in the title provided with 7 tables of comparative measuring are also disclosed. The results demonstrate that a new, easily produced, stable, medicinal preparation usable for all dosage forms is created. The biological activity of said preparation exceeds the biological activity of analogous preparations, and the range of pharmacological action thereof is non-specific and unusually large.
机译:本发明涉及医学,药理学以及化学和制药工业。本发明的目的是开发一种具有高活性并且具有上述非特异性药理作用范围大的新药物制剂,以及用于所有目前已知剂型的生产方法。本发明的新颖性在于该制剂的生物活性部分,其含有a啶酮乙酸或其衍生物与单糖的单取代醚的混合物,该生物活性部分与药学上可接受的载体一起在80℃的温度下进行了热处理。 ℃至120℃。含有ANANDIN的药物制剂显示出更高的效率。 ANANDIN以N- cri啶酮乙酸(葡糖氨基丙基咔ac啶酮)和3-0(N,N-二甲基氨基-正丙基)-1.2:5.6-二-O-异亚丙基-α,D-葡糖呋喃糖(二甲基氨基丙基葡糖呋喃糖)的混合物形式体现)。本发明的药物制剂以所有已知剂型的形式体现。还公开了用于制备该制剂及其剂型的六个系列的实施例,标题中列举了所有生物活性的实验估计的详细信息,并提供了七个比较测量表。结果表明,创造了可用于所有剂型的新的,易于生产的,稳定的药物制剂。所述制剂的生物活性超过类似制剂的生物活性,并且其药理作用范围是非特异性的并且异常大。

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