Use of an aromatase inhibitor for the preparation of pharmaceutical compositions for the treatment of hormone-dependent disorders by overexpression of HER2 protein and method to reduce undesirable effects of anticancer therapy

摘要

A method of treating a human being suffering from an hormone-dependent disorder characterized by the overexpression of HER2 comprising administering to said human being an aromatase inhibitor e.g. exemestane, fadrozole, letrozole and anastrozole and an antibody against HER2 e.g. trastuzumab, in amounts effective to produce a superadditive or synergistic therapeutic effect.