the use of adenosiini and its analogues for treatment of insulin resistance syndrome jadiabeedi product

摘要

The invention relates to the use of adenosine compounds described by formula I CHEM and certain derivatives thereof for producing a medicine for the treatment of the insulin resistance syndrome and diabetes. In the formula I K is N, N-O, or CH; Q is CH2 or O; R6 is hydrogen, alkyl, allyl, 2-methallyl, 2-butenyl, or cycloalkyl; CHEM E is O or S; Y is e.g. hydrogen, alkyl, aralkyl, aryl; n and p are independently 0, 1, 2, or 3, provided that n + p is at least 1; T is e.g hydrogen, alkyl, acyl, thioacyl, halo, carboxyl; R1, R2 and R3 are independently H, alkyl, or cycloalkyl; A is hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, or OR'; B is hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, or OR"; R' and R" are e.g independently hydrogen, alkyl, aralkyl or carbamoyl.