POLYMORPHIC FORMS OF 1-'4-(5-CYANOINDOL-3-YL)BUTYL-4-(2-CARBAMOYLBENZOFURAN-5-YL)PIPERAZINE HYDROCHLORIDE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

The present invention relates to novel crystal modifications of 1- [4- (5-cyanoindol-3-yl) butyl] -4- (2-carbamoylbenzofuran-5-yl) piperazine hydrochloride, 1- [4- (5-cyanoindole)]. 3-yl) butyl] -4- (2-carbamoylbenzofuran-5-yl) piperazine di (hydrogen chloride) crystal modifications and 1- [4- (5-cyanoindol-3-yl) butyl] -4- carbamoylbenzofuran-5-yl) piperazine hydrochloride amorphous forms which are particularly suitable for depressive disorders, anxiety disorders, bipolar disorder, mania, dementia, substance-related disorders, sexual dysfunction, eating disorders, obesity, fibromyalgia, sleep disorders, psychiatric disorders, brain heart attack, treatment and prophylaxis, or hypertension, brain disorders, chronic pain, acromegaly, hypogonadism, secondary amenorrhea, menstrual syndrome, and unwanted baby bedding for the manufacture of medicinal products for the prevention or prevention of t The invention includes the preparation of a new crystal modification and pharmaceutical compositions containing it. HE