首页> 外国专利> OPHTHALMIC COMPOSITION CONTAINING AN ION SENSITIVE, HYDROPHILIC POLYMER AND AN INORGANIC SALT IN A RATIO WHICH GIVES LOW VISCOSITY

OPHTHALMIC COMPOSITION CONTAINING AN ION SENSITIVE, HYDROPHILIC POLYMER AND AN INORGANIC SALT IN A RATIO WHICH GIVES LOW VISCOSITY

机译:粘度低的比例中包含离子敏感,亲水性聚合物和无机盐的眼科药物组合物

摘要

The present invention relates to an ophthalmic composition for topical application in the form of an aqueous solution for human and veterinary use; and the use of a solution, in particular for the treatment and prevention of glaucoma and high eye pressure. The composition of the present invention is an ophthalmic drug comprising essentially basic groups, from 0.004% to 1.5% by weight of an ion-sensitive, acid-containing hydrophilic polymer, from 0.01 to 2.0% by weight of total inorganic salt and buffer material, Contains 3.0 wt% wetting agent, - 0-0.02 wt% of preservative and water, and the salt and polymer components are in such proportions that the solution has a viscosity of less than 1000 mPa · s at a shear rate of 1.1 s -1 and the pH of the solution is between 4.0 and 8.0. ŕ
机译:本发明涉及用于人和兽医用途的水溶液形式的局部用眼用组合物。以及溶液的用途,特别是用于治疗和预防青光眼和高眼压。本发明的组合物是一种眼科药物,其包含基本上为碱性的基团,其为离子敏感的含酸的亲水性聚合物的0.004重量%至1.5重量%,占无机盐和缓冲材料的总量的0.01重量%至2.0重量%,包含3.0重量%的润湿剂,-0-0.02重量%的防腐剂和水,并且盐和聚合物成分的比例应使溶液在1.1 s -1的剪切速率下的粘度小于1000 mPa·s溶液的pH值在4.0至8.0之间。 ŕ

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