DUAL NON-SELECTIVE BETA-ADRENORECEPTOR AND ALPHA1-ADRENORECEPTOR ANTAGONIST FOR INHIBITING THE EXPRESSION OF FAS

摘要

PCT No. PCT/US97/14792 Sec. 371 Date Feb. 22, 1999 Sec. 102(e) Date Feb. 22, 1999 PCT Filed Aug. 22, 1997 PCT Pub. No. WO98/07321 PCT Pub. Date Feb. 26, 1998The present invention relates to a new method of treatment using compounds which are dual non-selective beta-adrenoceptor and alpha-1-adrenoceptor antagonists, in particularly the carbazolyl-(4)-oxypropanolainine compounds of Formula 1, as defined herein, for inhibiting the expression of Fas, a cell surface protein.