PROCESS FOR PREPARATION OF 1-ETHYL-4- {3-3-ETHYL- 6, 7-DIHYDRO-7- OXO-2- (PYRIDYLMETHYL) -2H- PYRAZOLO 4, 3-d PYRIMIDIN- 5-YL -4- PROPOXYSULFONYL}- PIPERAZINE AND THE 4-2-SUBSTITUTED-5-(4-ETHYL- 1-PIPERAZINYLSULPHONYL)- BENZAMIDO-5-ETHYL-1- (2-PYRIDYLMETHYL) 1H-PYRAZOLE-3-CARBOXAMIDE INTERMEDIATES THEREFOR

摘要

A process for the preparation of a compound of the formula 3761 כ" ז בשבט התשס" ד - February 19, 2004 comprising reacting a compound of the formula in the presence of -OR, wherein R is CH2 CH2CH3, where X is selected from the group consisting of arylsulphonyloxy, C4 alkylsulphonyloxy, nitro or halo substituted benzenesulphonyloxy, C1-C4 perfluoroalkylsulphonyloxy, optionally substituted aroyloxy, C1-C4 perfluoroalkanoyloxy, C1-C4 alkanoyloxy, halo, diazonium, methoxy, oxonium, perchloryloxy, quaternaryammonium C1-C4 alkylsulphonyloxy, halosulphonyloxy, halonium and diarysulphonylamino. Compounds of formula IIB are claimed as new.