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Norcholesterol, treatment fatty liver, the pharmaceutical composition for treating hyperglycemia and diabetes are prepared with cholic acid or bile salt fatty acid conjugates
Norcholesterol, treatment fatty liver, the pharmaceutical composition for treating hyperglycemia and diabetes are prepared with cholic acid or bile salt fatty acid conjugates
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机译:用胆酸或胆盐脂肪酸结合物制备降胆固醇,治疗脂肪肝,治疗高血糖和糖尿病的药物组合物
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摘要
Use of a bile acid or bile salt fatty acid conjugate of general formula II W-X-G in which G is a bile acid or bile salt radical, which, if desired, is conjugated in position 24 with an amino acid, W stands for one or two fatty acid radicals having 14-22 carbon atoms and X stands for a suitable bonding member or for a direct C=C bond between said bile acid or bile salt radical and the fatty acid(s) or of a phannaceutical composition comprising same for the manufacture of a medicament for the reduction of the cholesterol in blood and for the treatment of hyperglycemia and diabetes, wherein said suitable bonding member provides a solid bond that is not substantially deconjugated during the absorption process of the conjugate.
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