Use of 2-amino-3,4-dihydro-quinazolines for producing a medicament for treating or preventing diseases caused by ischaemic conditions

摘要

The application discloses the use of the compound formula I (see below) or of its pharmaceutically tolerable salts where: R1 and R2 are hydrogen, F, Cl, Br, I strain-chain or branched C1-C4-alkyl, C1-C4-alkoxy, R3 is hydrogen, straight chain or branched C1-C4-alkyl or phenyl, the phenyl nucleus being unsubstituted or carrying one to three substituents selected from the group consisting of F, Cl, CH3 and CH3O. Formula I maybe used for the production of a medicament for the therapy of prophylaxis of ischemic conditions including, cardiac infarct, angina pectoris, and ischemic conditions of peripheral organs and limbs. It may also be used to formulate medicaments for the treatment of states of shock, for surgical operations and organ transplantation, to treat illness in which cell proliferation is a primary or secondary cause and treat prophylaxis of disorders of fat metabolism. Alternatively it may be used for the production of a medicament for the preservation and storage of transplants for surgical measures