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A method for use of carbamate enantiomers in preventing or treating neuropathic pain and cluster and migraine headache-associated pain

机译:一种氨基甲酸酯对映体在预防或治疗神经性疼痛以及与丛集性和偏头痛相关的疼痛中的用途的方法

摘要

Use of a therapeutically effective amount of an enantiomer of formula (I) substantially free of other enantiomers or an enantiomeric mixture for preventing or treating neuropathic pain and cluster and migraine headache-associated pain is disclosed, wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and R1 and R2 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
机译:公开了治疗有效量的基本上不含其他对映异构体或对映异构体混合物的式(I)对映异构体用于预防或治疗神经性疼痛和丛集性和与偏头痛相关的疼痛的用途,其中苯基在X处被1-5取代卤素原子独立地选自氟,氯,溴和碘; R1和R2独立地选自氢和C1-C4烷基。其中C1-C4烷基任选地被苯基取代(其中苯基任选地被独立地选自氢,卤素,C1-C4烷基,C1-C4烷氧基,氨基,硝基和氰基的取代基取代)。

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