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Particulate composition of eletriptan showing a sigmoidal pattern of controlled release.
Particulate composition of eletriptan showing a sigmoidal pattern of controlled release.
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机译:依曲曲普坦的颗粒组成显示出缓释的S型曲线。
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摘要
The invention provides a pharmaceutical composition in particulate form, suitable for oral administration, including a core containing eletriptan or a pharmaceutically acceptable salt thereof, the core being coated with a water-insoluble, permeable coating including one or more acrylic copolymer(s) containing trimethylammoniumethylmethacrylate groups, said composition being capable of achieving a sigmoidal pattern of controlled drug release. Such a pharmaceutical composition is particularly useful in the prevention of migraine recurrence.
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