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Procedures to reduce the incidence of Stillborn Pigs through the use of antagonists of the progesterone receptor

机译:通过使用孕激素受体拮抗剂来减少死胎的发生率的程序

摘要

Refers to a procedure for Inducing parturition in sows Prenadas, which will result in the Birth of the first Breeding in a predictable number of hours between 12 hours and 22 hours.The process comprises: (1) the Administration of a progesterone receptor antagonist Prenadas sows that are at least 112 days after mating, the antagonist, selected from: ru38486, zk230211, zk98299, zk98774, zk137316, zk112993, j867, j956, lgoo1447, lg120753 , org33628, mifepristone and lilopristone onapristone, combinations thereof,Which can be administered once or twice, between the Single Dose of approximately 0.001 mg / kg, and 15 mg / kg body weight and Applied 20 to 25 hours before birth and in the first two Administrations, is 30 to 40 hours before birth and the second approximately 9 to 15 Hours before birth
机译:指诱导Prenadas母猪分娩的程序,该程序可在12小时至22小时的可预测小时数内导致首次繁殖。该过程包括:(1)孕激素受体拮抗剂Prenadas母猪的给药。在交配至少112天后,拮抗剂选自:ru38486,zk230211,zk98299,zk98774,zk137316,zk112993,j867,j956,lgoo1447,lg120753,org33628,米非司酮和利洛普司酮onapristone,其组合,可一次给药在大约0.001 mg / kg体重的单剂和15 mg / kg体重的单剂量之间或两次给药之间,在出生前20至25小时和头两次给药,分别在出生前30至40小时和第二次大约9给药到出生前15小时

著录项

  • 公开/公告号PE04022004A1

    专利类型

  • 公开/公告日2004-06-26

    原文格式PDF

  • 申请/专利权人 PFIZER PRODUCTS INC.;

    申请/专利号PE20030000962

  • 发明设计人 GAYNOR PAULA JOAN;MANN DOUGLAS DANE;

    申请日2003-09-19

  • 分类号A61K31/569;A61P15/04;

  • 国家 PE

  • 入库时间 2022-08-21 23:09:11

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