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REDOX REVERSIBLE HCV PROTEINS WITH NATIVE-LIKE CONFORMATION
REDOX REVERSIBLE HCV PROTEINS WITH NATIVE-LIKE CONFORMATION
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机译:具有天然结构的氧化还原可逆丙型肝炎病毒蛋白
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摘要
The present invention relates to HCV proteins in which cysteine residues are reversibly protected during purification. Eventually, this purification procedure results in HCV proteins with biological activity and a native-like protein conformation, which present corresponding epitopes. The present invention pertains also to drug screening methods using these HCV proteins, and diagnostic and therapeutic applications, such as vaccines and drugs.
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